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If there is one disease that captures the classic epidemiological triad of agent, host and environment, it is malaria, which has been a scourge for centuries. This World Malaria Day, which falls on 25 April, invites us to tackle the menace with new vigour with its theme: "End malaria for good." However, more of the same old solutions will definitely not meet the goal. Here I'm proposing a framework of solutions with 10 pillars. Think of them as commandments, if you will.